hrp0082p3-d1-977 | Thyroid | ESPE2014

Neonatal Thyrotoxicosis in Maternal Grave’s Disease: a Case Series and Review of the Literature

Johnston Niall , Mavinjurve Meenal , Murphy Nuala , McDonnell Ciara , Moloney Sinead , Cody Declan , Costigan Colm

Background: Neonatal thyrotoxicosis, a rare and life-threatening condition, is caused by transplacental transfer of thyroid stimulating immunoglobulins from mother to infant. While clinical features may include goitre, prominent eyes and poor weight gain, these may be absent in some cases. Early diagnosis and treatment of affected infants is critical.Objective: We report a case series of infants with neonatal thyrotoxicosis from two tertiary paediatric h...